Olanzapine research papers - Quality Academic Writing.

Olanzapine can induce cardiomyopathy in selected patients. Taken together, all mentioned data indicate that interventions aimed at the amelioration of obesity and cardiovascular illness need to be.

Olanzapine is principally metabolized by glucuronidation, with a smaller metabolic contribution from the cytochrome oxidase system. Adverse effects of olanzapine include somnolence, postural hypotension, constipation, dizziness, restlessness, and weight gain. The purpose of this article is to outline the pharmacodynamics, pharmacology, and evidence for the use of olanzapine in palliative care.

Introduction. Olanzapine is an antipsychotic agent with a favourable safety profile, and has greater promise among nonresponders when compared with the conventional antipsychotic drug, haloperidol ().Olanzapine is well absorbed following oral administration in both the fed and fasted states, and is extensively metabolized with higher clearance in males than in females ().

Papers Assessment of independent effect of olanzapine and risperidone on risk of diabetes among patients with schizophrenia: population based nested case-control study.

Olanzapine also showed to have a reduction in extrapyramidal symptoms and an increase in neurocognitive functioning, response rates, compliance, and quality oflife. However, olanzapine did have negative side effects such as: significant weight gain, increase in blood pressure and cholesterol, and a decrease in liver function.

The OPTiMiSE cohort included 446 patients with DUP up to two years, who were administered amisulpride for 4 weeks (Phase I). Patients who did not meet Andreasen remission criteria were randomized to double-blind continuation of amisulpride or olanzapine for 6 additional weeks in a blinded study (Phase II).

Practice: The authors stated that caregivers should follow carefully how and when to use IM olanzapine. Research: The authors stated that more studies are needed to further clarify issues regarding safety and efficacy of IM olanzapine, and that future studies should also focus on investigating how the drug interacts with other medications.

Clinical improvement, defined as a 20% reduction in total scores of SAPS and SANS, was seen, respectively, in 86.66% and 56.66% of the cases in the olanzapine group and 73.33% and 36.66% of them in the risperidone group at the end of the assessment.

International Journal of Pharmacology and Clinical Sciences (Int. J. Pharm. Clin Sci) ISSN: 2278-0068 Aim and Scope. The International Journal of Pharmacology and Clinical Sciences is an official journal of Glorious Future Institution for Trade based in Saudi Arabia; A Quarterly Open access journal aim to publish Latest Research, Important Reviews, Useful guidelines, topics related Total.

They are tolerated well. However, in certain patient populations, they are associated with SIADH (Syndrome of Inappropriate Anti-Diuretic Hormone Secretion) and Hyponatremia. Various research studies have shown that all antidepressants are associated with Hyponatremia. Hyponatremia as a side effect of antidepressant therapy is more commonly.

Olanzapine showed a low motor side effect profile. This profile was similar but not identical to what has already been described with clozapine. Moreover, olanzapine failed to show the spectrum of severe drug side effects typically associated with clozapine; these include agranulocytosis, drooling, seizures, tachycardia, and severe sedation.

A sad and troubling case to be sure. What seems less obvious is the role of a withdrawal syndrome in Sally’s symptoms. While exact dates are not given, apparently about 2 months elapse between the complete termination of olanzapine administration and the onset of symptoms.